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Jang, In-Jin
Department

Clinical Pharmacology and Therapeutics

Specialty

Pharmacogenomics , Clinical drug development , Drug Side Effects , Therapeutic drug monitoring

Appointment

Education / Career

Education / Career
Article Pharmacokinetic interactions between fexuprazan, a potassium-competitive acid blocker, and nonsteroidal anti-inflammatory drugs in healthy males
Announcements Clin Transl Sci Date of publication 202405
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38700290/
Education / Career
Article Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea
Announcements Clin Transl Sci Date of publication 202403
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38501281/
Education / Career
Article Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects
Announcements Clin Transl Sci Date of publication 202403
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38436494/
Education / Career
Article Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
Announcements Exp Mol Med Date of publication 202403
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38424191/
Education / Career
Article Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects
Announcements Drug Des Devel Ther Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38352172/
Education / Career
Article Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects
Announcements Clin Pharmacol Drug Dev Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38156730/
Education / Career
Article Effects of food and ethnicity on the pharmacokinetics of venadaparib, a next-generation PARP inhibitor, in healthy Korean, Caucasian, and Chinese male subjects
Announcements Invest New Drugs Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38099989/
Education / Career
Article Topiramate dosage optimization for effective antiseizure management via population pharmacokinetic modeling
Announcements Ann Clin Transl Neurol Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38062636/
Education / Career
Article Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial
Announcements EClinicalMedicine Date of publication 202309
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37711219/
Education / Career
Article Semimechanistic pharmacokinetic-pharmacodynamic model of tripegfilgrastim for pediatric patients after chemotherapy
Announcements CPT Pharmacometrics Syst Pharmacol Date of publication 202309
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37559343/
Education / Career
Article Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed-release formulations
Announcements Br J Clin Pharmacol Date of publication 202309
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37170677/
Education / Career
Article A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects
Announcements Drug Des Devel Ther Date of publication 202304
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37113469/
Education / Career
Article Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl-tRNA synthetase inhibitor, in healthy subjects
Announcements Clin Transl Sci Date of publication 202307
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37095713/
Education / Career
Article Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects
Announcements Drug Des Devel Ther Date of publication 202304
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37077412/
Education / Career
Article Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed-Release Formulation of Esomeprazole in Healthy Subjects
Announcements Clin Pharmacol Drug Dev Date of publication 202308
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36929154/
Education / Career
Article Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole
Announcements Clin Pharmacokinet Date of publication 202304
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36897544/
Education / Career
Article Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin
Announcements Diabetes Obes Metab Date of publication 202306
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36852751/
Education / Career
Article Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects
Announcements Pharmaceutics Date of publication 202302
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36839870/
Education / Career
Article pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers
Announcements Clin Transl Sci Date of publication 202303
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36514192/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Interaction of DWP16001, an SGLT2 Inhibitor, with Gemigliptin and Metformin in Healthy Adults
Announcements Br J Clin Pharmacol Date of publication 202306
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36496349/
Education / Career
Article Evaluation of drug prescribing patterns and therapeutic drug monitoring practice using electronic medical records
Announcements Sci Rep Date of publication 202212
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36494483/
Education / Career
Article Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects
Announcements Br J Clin Pharmacol Date of publication 202304
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36422809/
Education / Career
Article Safety, tolerability, and serum/tear pharmacokinetics of human recombinant epidermal growth factor eyedrops in healthy subjects
Announcements Pharmaceuticals (Basel) Date of publication 202210
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36355484/
Education / Career
Article A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population
Announcements Exp Mol Med Date of publication 202211
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36323850/
Education / Career
Article Safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of Vutiglabridin: a first-in-class, first-in-human study
Announcements Clin Transl Sci Date of publication 202211
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36176051/
Education / Career
Article Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects
Announcements Front Pharmacol Date of publication 202208
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36071831/
Education / Career
Article Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination
Announcements Transl Clin Pharmacol Date of publication 202206
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35800670/
Education / Career
Article The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects
Announcements Clin Transl Sci Date of publication 202209
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35727711/
Education / Career
Article Dose-dependent glucosuria of DWP16001, a novel selective sodium-glucose cotransporter-2 inhibitor, in healthy subjects
Announcements Br J Clin Pharmacol Date of publication 202209
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35395697/
Education / Career
Article Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole
Announcements British journal of clinical pharmacology. Date of publication 202207
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35146797/
Education / Career
Article Single-dose of LC51-0255, a selective S1P 1 receptor modulator, showed dose-dependent and reversible reduction of absolute lymphocyte count in humans
Announcements Clinical and translational science. Date of publication 202204
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35045208/
Education / Career
Article A Phase 1 Study to Evaluate the Safety and Pharmacokinetics following Administration of Single and Multiple Doses of the Anti-Staphylococcal Lysin, LSVT-1701, in Healthy Adult Subjects
Announcements Antimicrobial agents and chemotherapy. Date of publication 202203
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35007129/
Education / Career
Article Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole
Announcements Drug design, development and therapy. Date of publication 202112
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34992346/
Education / Career
Article Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
Announcements Clin Transl Sci Date of publication 202112
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34863048/
Education / Career
Article Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese
Announcements Clin Transl Sci Date of publication 202110
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34670008/
Education / Career
Article Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects
Announcements Clin Transl Sci Date of publication 202110
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34664769/
Education / Career
Article Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform
Announcements Transl Clin Pharmacol Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34621706/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors
Announcements Clin Pharmacol Ther Date of publication 202201
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34605552/
Education / Career
Article Prediction of Drug-Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation
Announcements Pharmaceutics Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34575565/
Education / Career
Article A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults
Announcements Clin Transl Sci Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34523814/
Education / Career
Article The necessary conduct: Exploratory multiregional clinical trials in East Asia
Announcements Clin Transl Sci Date of publication 202111
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34397152/
Education / Career
Article Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids
Announcements Diabetes Res Clin Pract Date of publication 202108
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34329692/
Education / Career
Article Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects
Announcements Drug Design, Development and Therapy Date of publication 202106
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34103898/
Education / Career
Article Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP�) Biosimilar, to Those of NESP� After a Single Subcutaneous or Intravenous Administration to Healthy Subjects
Announcements Drug Des Devel Ther. Date of publication 202104
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33953543/
Education / Career
Article Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK-30, and From Red Ginseng Extract in Healthy Korean Subjects
Announcements Clin Pharmacol Drug Dev. Date of publication 202111
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33884767/
Education / Career
Article Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/ hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects
Announcements Transl Clin Pharmacol Date of publication 202103
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33855001/
Education / Career
Article Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy
Announcements Sci Rep. Date of publication 202103
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33737678/
Education / Career
Article Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing
Announcements Transplantation Date of publication 202110
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33654003/
Education / Career
Article Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan
Announcements Clin Pharmacol Drug Dev. Date of publication 202111
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33647189/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study
Announcements Drug Des Devel Ther Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33628012/
Education / Career
Article Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects
Announcements Clinical therapeutics. Date of publication 202103
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33518355/
Education / Career
Article Pharmacokinetic Equivalence of CT-P17 to High-Concentration (100 mg/mL) Reference Adalimumab: A Randomized Phase I Study in Healthy Subjects
Announcements Clinical and translational science. Date of publication 202107
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33503313/
Education / Career
Article Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes
Announcements TCP Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33425803/
Education / Career
Article Pharmacogenomic information from CPIC and DPWG guidelines and its application on drug labels
Announcements Transl Clin Pharmacol Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33425802/
Education / Career
Article Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers
Announcements Clin Transl Sci Date of publication 202105
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33382926/
Education / Career
Article Effect of Meal Timing on Pharmacokinetics and Pharmacodynamics of Tegoprazan in Healthy Male volunteers
Announcements Clin Transl Sci Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33382926/
Education / Career
Article The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348240/
Education / Career
Article Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348239/
Education / Career
Article Tolerability of lacosamide rapid dose titration: A randomized, multicenter, prospective, open-label study
Announcements Epilepsy Behav Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33342710/
Education / Career
Article Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy
Announcements Epilepsy Behav Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33328106/
Education / Career
Article Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects
Announcements Drug Des Devel The Date of publication 202011
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33262578/
Education / Career
Article A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators
Announcements Pharmacogenetics and genomics. Date of publication 202104
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33165168/
Education / Career
Article Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects
Announcements Aliment Pharmacol Ther Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33131095/
Education / Career
Article Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects
Announcements Drug Des Devel The Date of publication 202010
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33122892/
Education / Career
Article Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities
Announcements Aliment Pharmacol Ther Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33111337/
Education / Career
Article Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects
Announcements Br J Clin Pharmacol Date of publication 202104
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33047859/
Education / Career
Article Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers
Announcements Pharmacogenomics J Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32461666/
Education / Career
Article Usefulness of saliva for perampanel therapeutic drug monitoring. in Epilepsia has the following publication status
Announcements Epilepsia Date of publication 202006
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32378757/
Education / Career
Article Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin With Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers
Announcements Drug Des Devel Ther Date of publication 202002
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32109991/
Education / Career
Article Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles.
Announcements Scientific reports Date of publication 202002
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32071370/
Education / Career
Article Impact of vancomycin-induced changes in the intestinal microbiota on the pharmacokinetics of simvastatin.
Announcements Clin Transl Sci Date of publication 202007
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32058642/
Education / Career
Article Artificial intelligence in drug development: clinical pharmacologist perspective
Announcements TCP Date of publication 201909
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32055587/
Education / Career
Article Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.
Announcements Scientific reports Date of publication 201912
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31857620/
Education / Career
Article Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population.
Announcements Scientific reports. Date of publication 201911
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31690757/
Education / Career
Article Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis
Announcements Cancers Date of publication 201910
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31590436/
Education / Career
Article Safety, tolerability, and anti-tumor activity of olmutinib in non-small cell lung cancer with T790M mutation: A single arm, open label, phase 1/2 trial.
Announcements Lung cancer Date of publication 201909
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31447004/
Education / Career
Article ST2 blockade mitigates peritoneal fibrosis induced by TGF-β and high glucose.
Announcements J Cell Mol Med Date of publication 201910
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31397957/
Education / Career
Article Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea.
Announcements Chinese clinical oncology. Date of publication 201906
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31311281/
Education / Career
Article A safety, pharmacokinetic, pharmacogenomic and population pharmacokinetic analysis of the third-generation EGFR TKI, olmutinib (HM61713), after single oral administration in healthy volunteers.
Announcements Basic Clin Pharmacol Toxicol Date of publication 201905
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31125491/
Education / Career
Article Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.
Announcements Drug metabolism and pharmacokinetics Date of publication 201908
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31088714/
Education / Career
Article Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry.
Announcements Journal of Korean medical science (JKMS) Date of publication 201904
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30950250/
Education / Career
Article Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways
Announcements Metabolomics Society Date of publication 201902
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30830474/
Education / Career
Article A Personalized CYP2C19 Phenotype-Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis
Announcements Journal of clinical medicine Date of publication 201902
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30744151/
Education / Career
Article Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment
Announcements JOURNAL OF KOREAN MEDICAL SCIENCE Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30595680/
Education / Career
Article Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.
Announcements Genomics & Informatics Date of publication 201811
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30309203/
Education / Career
Article Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction
Announcements SCIENTIFIC REPORTS Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30089798/
Education / Career
Article The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs
Announcements ALLERGY ASTHMA & IMMUNOLOGY RESEARCH Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30088374/
Education / Career
Article Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30087555/
Education / Career
Article Favorable Outcome of Post-Transplantation Cyclophosphamide Haploidentical Peripheral Blood Stem Cell Transplantation with Targeted Busulfan-Based Myeloablative Conditioning Using Intensive Pharmacokinetic Monitoring in Pediatric Patients
Announcements BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION Date of publication 201811
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29981849/
Education / Career
Article Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects
Announcements EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Date of publication 201810
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29907887/
Education / Career
Article Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects
Announcements ALIMENTARY PHARMACOLOGY & THERAPEUTICS Date of publication 201807
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29863280/
Education / Career
Article Assessment of induced CYP3A activity in pregnant women using 4 beta-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker
Announcements DRUG METABOLISM AND PHARMACOKINETICS Date of publication 201806
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29759884/
Education / Career
Article Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29750017/
Education / Career
Article The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers
Announcements EUROPEAN NEUROPSYCHOPHARMACOLOGY Date of publication 201805
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29567399/
Education / Career
Article Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29497279/
Education / Career
Article Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201711
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29158665/
Education / Career
Article Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects
Announcements JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29069400/
Education / Career
Article Identification of - or (-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity
Announcements CLINICAL PHARMACOLOGY & THERAPEUTICS Date of publication 201805
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28877336/
Education / Career
Article Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects
Announcements CLINICAL THERAPEUTICS Date of publication 201709
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28865799/
Education / Career
Article Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram
Announcements BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY Date of publication 201802
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28834212/

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